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KMID : 0032220220340030225
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Annals of Dermatology
2022 Volume.34 No. 3 p.225 ~ p.227
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Intralymphatic Histiocytosis Associated with Osteoarthritis: A Case Report
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Koo Tae-Han
Kang Hyun-Ji
Kim Min-Soo
Jue Mihn-Sook
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Abstract
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Intralymphatic histiocytosis (ILH) is a rare cutaneous condition with uncertain pathogenesis. It is characterized by dilated lymphatic vessels that contain histiocytes within their lumina. Although the etiology of ILH remains unknown, it has been associated with various inflammatory and neoplastic diseases, such as rheumatoid arthritis (RA), reaction to metal joint implants and Merkel cell carcinoma, breast cancer and colon cancer. An 83-year-old female presented with an erythematous patch on the left forearm that had appeared six months previous. She had suffered from osteoarthritis (OA) and the cutaneous lesion was located in the vicinity of the affected joint. Skin biopsy from the lesion showed dilated dermal vessels and some ectatic vessels that contained many mononuclear histiocytes. Based on the clinical and histopathological findings, we diagnosed her with ILH with OA. Two sessions of intralesional triamcinolone acetonide injection (5 mg/ml) were administered to treat the skin lesion, which gradually improved over a period of a few months. We here report a rare case of ILH associated with degenerative OA.
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KEYWORD
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Intralymphatic histiocytosis, Osteoarthritis
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